Profibus (Process Field Bus) is a standard protocol, which is developed firstly in Germany in 1987, and later became European and international standard protocol. After international normalizing, protocol Profibus becomes the most popular application in the system of industrial communication protocols, with over 1000 members and over 20 percent world market share. In this paper, the author would like to present some basic characteristics of Profibus protocol and some specific actual application of Profibus DP in the control and automation system.