During the implementation process of industrialization and modernization of agriculture and rural development, the years, the authorities and industry in the province has focused on directing and implementing the research and application of science and technology for rural development sustainable, creating a foundation to promote economic development - local economic development. The paper studies the application of scientific and technical progress in rice production in Thai Nguyen and find out the achievements, constraints and reasons in the application of science and technology in agricultural development in the country today.