The purpose of this study was to evaluate the relationship between the urine albuminl creatinine ratios with the following biochemical parameters: blood glucose, HbA1c, blood lipids, glomerular filtration rate in diabetic patients. A descriptive cross-sectional study included type 2 diabetic patients, diagnosed according to of American Diabetes Association criteria 2012. 177 patients of type 2 diabetes were tested for urine albumin/creatinine ratio to assess its relationship with the biochemical parameters. Results showed that ACR was related to increased fasting blood glucose (OR: 1.2, 95 percent CI: 1.1 - 3.9) and HbA1c (OR: 2.7, 95 percent CI: 1,4 - 5.2). No correlation between random urine ACR with cholesterol, triglycerides and LDL - cholesterol in the study subjects (p 0.05). There was a negative collation between randomized urine ACR and glomerular filtration rate (p 0.001). There was an association between serum creatinine concentration and random urine ACR (p 0.05). There was no correlation between random urine ACR with age, gender and duration of diabetes (p 0.05). Urine albumin/creatinine is a reliable test for monitoring and screening for renal complications in patients with diabetes.