Dehydrins (DHN) belong to Group II of Late Embryogenesis Abundant protein (LEA). These proteins play a crucial role in protecting cells against the adverse effects of environmental stress by increasing water retention capacity. They are also important in membrane and molecule protection. In this study, the authors identified six DHN genes in the Sesame genome (Sesamum indicum L.). All of these DHN proteins contain the K-segment which was characterized in all previously reported DHN proteins. Based on the results of conserved motif analysis as well as phylogenetic tree analysis, six sesame DHN genes were classified into three subgroups of YnSKn (two genes), SKn (two genes) and KS (one gene). The result of the expression study shows that sesame contains at least three DHN expressed genes in its developing seed.