Objective: To study anatomy of the perforating thoracodorsal artery and its clinical application. Subject and method: From 2012-2013, the authors conducted a study at the Anatomy Department, Ho Chi Minh University of Medicine and Pharmacy with 16 cadaver specimens, 32 areas of the perforating thoracodorsal artery bilaterally and 36 images of the artery under DSA (Digital Substraction Angiography). Result: In DSA, thoracodorsal artery were mostly originated from subscapular artery in 29 of 36 cases (80.6 percent). In cadaveric dissection, the artery were originated from subscapular artery in 29 of 32 cases (90.6 percent), the remaining 3/32 cases were originated from axilary artery (9.4 percent). Diameter and length of the thoracodosal artery were 2.64 +/- 0.51 mm and 4.95 +/- 0.99cm, respectively. The number of the perforating arteries were 83, with average of 2.6 perforating arteries in each anatomical preparation (minimum 1 branch, maximum 4 branches). Diameter and length of the TAP was 1.03 +/- 0.25mm and 3.23 +/- 0.78cm, respectively. Distance from the umblical artery to the TAP was 4.74 +/- 0.81cm, to the anterior border of latissimus dorsi muscles was 2.47 +/- 0.64cm, and to lower boder of axillary flexura was 6.72 +/- 1.32cm. Conclusion: Perforating thoracodorsal artery is constant with large dimensions and so that can be clinically applicable.