The study were carried out and analyzed on 106 in-patients and 560 out-patients. The structure of drug use in Hospital A Thai Nguyen province in 2013. It's show that 22 of drug group in 226 active compound , 5 drug groups consumed much value as anti-bacteria, parasites (39.5 percent) , hormone and endocrine drugs (15.7 percent ) , gastrointestinal (10.0 percent ) , cardiovascular drugs (8.9 percent ) and drug effects on the blood of 7.1 percent. Percentage of single- ingredient drugs account for 85.1 percent of all, and 82.7 percent of economic value. Local drugs accounts for 48.5 percent and 28.1 percent of the value. There are 51.5 percent of imported drugs account, 71.9 percent of economic value.