Two-dimensional (2D) semiconductors hold significant potential for the fabrication of self-powered reconfigurable devices due to their atomically thin body thickness and excellent heterogeneous integration capabilities. Despite these advantages, regulating polarity in 2D semiconductors remains challenging, and their complex heterostructures hinder practical applications. Here, we demonstrate a metal-semiconductor-metal (MSM) two-terminal structure to achieve self-powered and multiple reconfigurable functions in MoS