Artesunate Inhibits the Proliferation and Migration of Cutaneous Squamous Cell Carcinoma by Regulating the SLC7A11-GPX4 Pathway via the p300-p53 Axis.

• Tác giả: Jihui Huang, Xinyan Huang, Lili Li, Wenxi Wang, Songzhao Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 127 The unconscious and the subconscious
• Thông tin xuất bản: Korea (South) : Biomolecules & therapeutics , 2025
• Bộ sưu tập: NCBI
• ID: 657233

Tóm tắt

The incidence of cutaneous squamous cell carcinoma (CSCC) is increasing rapidly. This study discussed the effects of artesunate (ART) on CSCC cell proliferation and migration via the solute carrier family 7 member 11 (SLC7A11)-glutathione peroxidase 4 (GPX4) pathway. MTT assessed cell viability and analyzed the IC