Reagent-assisted regio-divergent cyclization synthesis of pyrazole.

• Tác giả: Mengdi Pang, Ali Ramazani, Guoying Zhang, Zhengguo Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 242.34 Lent
• Thông tin xuất bản: England : Organic & biomolecular chemistry , 2025
• Bộ sưu tập: NCBI
• ID: 662481

Tóm tắt

The present study reveals a practical one-pot base-promoted regio-divergent cyclization of hydrazines with alkynyl silane under mild conditions, facilitating the synthesis of diverse silicone-substituted pyrazoles and functionalized pyrazoles in great yields with exceptional selectivity. This protocol is expected to afford a streamlined one-pot approach for the synthesis of multiple compounds in water.