Enantiomeric fraction evaluation for assessing septic tanks as a pathway for chiral pharmaceuticals entering rivers.

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Tác giả: Elise Cartmell, Bruce Petrie, Vera Jemina Sundström, Kai Wilschnack, Kyari Yates

Ngôn ngữ: eng

Ký hiệu phân loại: 004.338 Systems analysis and design, computer architecture, performance evaluation of real-time computers

Thông tin xuất bản: England : Environmental science. Processes & impacts , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 663256

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Septic tanks (STs) are an important pathway for chiral pharmaceuticals entering rivers. Therefore, the enantiospecific compositions of 25 chiral human pharmaceuticals and metabolites were investigated in five community STs over 12 months in Scotland. Large variability in pharmaceutical concentrations and enantiomeric fractions (EFs) were observed in wastewater owing to the small contributing populations. Pharmaceuticals prescribed in enantiopure and racemic forms had the greatest EF variability. For example, citalopram generally had EFs <
0.5 through consumption of the racemate and preferential metabolism of

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