Fyn is classified as a member of the Src family of kinases (SFKs), a group of non-receptor tyrosine kinases. It is a critical component of many fundamental central nervous system (CNS) processes. Recently, a connection has been shown between Fyn malfunction and the pathogenic processes exhibited in neurodegenerative conditions, such as Alzheimer's disease (AD), which is a significant factor in worldwide mortality and disability. Due to the rising demographic of elderly individuals, there is a projected increase in incidence of AD in the forthcoming years. This study aims to identify prospective phytochemicals that can be utilized in developing a new protein kinase inhibitor for the therapeutic intervention of AD. The lack of therapeutic interventions capable of preventing the progression of AD is a significant concern thus, it is imperative to identify potential targets. This study employed a virtual screening approach to discover potential Fyn-kinase inhibitors from