CgA

• Tác giả: Arne Åsberg, Lena Løfblad, Gustav Mikkelsen
• Ngôn ngữ: eng
• Ký hiệu phân loại: 025.3496 Bibliographic analysis and control
• Thông tin xuất bản: England : Scandinavian journal of clinical and laboratory investigation , 2025
• Bộ sưu tập: NCBI
• ID: 663426

Tóm tắt

The concentration of chromogranin A in serum (s-CgA) is a general marker of neuroendocrine neoplasms. Unfortunately, s-CgA is increased in several other clinical conditions, including renal failure. The physician who assesses s-CgA values must consider the patients' renal function. How this should be done is not clear. We developed an adjustment formula from the association between median s-CgA and the estimated glomerular filtration rate (eGFR) in 2708 patients where s-CgA was measured by the CgA II KRYPTOR method. We used multivariable fractional polynomial quantile regression with the model ln(s-CgA) = c