Global burden of vaccine-associated kidney injury using an international pharmacovigilance database.

• Tác giả: Ahhyung Choi, Hyeon Seok Hwang, Kyunghwan Jeong, Hyeon Jin Kim, Jin Sug Kim, Min Seo Kim, Andreas Kronbichler, Hayeon Lee, Jinseok Lee, Masoud Rahmati, Jae Il Shin, Ju-Young Shin, Dong Keon Yon, Soo-Young Yoon
• Ngôn ngữ: eng
• Ký hiệu phân loại: 523.855 Globular clusters
• Thông tin xuất bản: England : Scientific reports , 2025
• Bộ sưu tập: NCBI
• ID: 66370

Tóm tắt

Global evidence on the association between vaccines and renal adverse events (AEs) is inconclusive. This pharmacovigilance study analyzed a total of 120,715,116 reports from VigiBase collected between 1967 and 2022. We evaluated the global reporting of acute kidney injury (AKI), glomerulonephritis (GN), and tubulointerstitial nephritis (TIN) and assessed disproportionate signals between vaccines and renal AEs using reporting odds ratios (ROR) and the lower limit of the 95% confidence interval of the information component (IC