Enhancing Implantable Medical Devices: Surface Functionalization of Titanium with Quaternary Ammonium Salts for Antibacterial Adhesion Properties.

• Tác giả: Consuelo Celesti, Alessio Facciolà, Bartolo Gabriele, Daniela Iannazzo, Antonio Laganà, Raffaella Mancuso, Elpida Piperopoulos, Giuseppa Visalli
• Ngôn ngữ: eng
• Ký hiệu phân loại: 338.04 Entrepreneurship
• Thông tin xuất bản: United States : ACS omega , 2025
• Bộ sưu tập: NCBI
• ID: 667446

Tóm tắt

Bacterial colonization of titanium-based materials used in implantable medical devices represents a significant challenge in the dental and orthopedic fields, often leading to infections and implant failure. This study reports the surface modification of titanium discs with ammonium salts containing carbon atom chains of different lengths (from 6 to 12) to provide antibacterial properties to the modified metal surfaces while maintaining their biocompatibility. The chemically modified samples have been characterized by ATR-FTIR and SEM-EDX analyses and evaluated for roughness and hydrophilic behavior. This surface modification not only provides hydrophobic properties to titanium surfaces but also introduces a hindering environment for bacterial adhesion. Antibacterial tests performed against methicillin-sensitive and methicillin-resistant