Synthetic photoresponsive hydrogels enable

• Tác giả: Kristi S Anseth, Michael R Blatchley, Peter J Dempsey, Bruce E Kirkpatrick, Colter E Oroke, Mark W Young
• Ngôn ngữ: eng
• Thông tin xuất bản: Germany : Advanced functional materials , 2025
• Bộ sưu tập: NCBI
• ID: 668751

Tóm tắt

As a model of the intestinal epithelium, intestinal stem cells (ISCs) have been grown and differentiated as monolayers on materials where stochastic organization of the crypt and villi cells occurs. We developed an allyl sulfide crosslinked photoresponsive hydrogel with a shear modulus of 1.6 kPa and functionalized with GFOGER, Bm-binder peptide ligands for monolayer growth of ISCs. The allyl sulfide chemistry allowed