Metabolomic Signatures in Adults with Metabolic Syndrome Indicate Preclinical Disruptions in Pathways Associated with High-Density Lipoprotein Cholesterol, Sugar Alcohols.

• Tác giả: Bradley Aouizerat, Elena Flowers, Alka M Kanaya, K A Lewis, Kayla D Longoria, Benjamin M Stroebel
• Ngôn ngữ: eng
• Ký hiệu phân loại: 070.48346 Journalism
• Thông tin xuất bản: United States : Research square , 2025
• Bộ sưu tập: NCBI
• ID: 669291

Tóm tắt

Background Metabolic syndrome is a pressing public health issue and risk factor for the development of type 2 diabetes (T2D) and cardiovascular disease (CVD), yet clinical practice is lacking in biomarkers that represent pre-clinical perturbations of the heterogenous subtypes of risk. This study aimed to characterize the baseline metabolome in relation to known clinical characteristics of risk in a sample of obese adults. Methods Untargeted metabolome data from