Exogenous cystine increases susceptibility of drug-resistant

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Tác giả: Junyuan Du, Binghu Fang, Zhiyi Wu, Heng Yang, Feike Zhao, Chunyang Zhu

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: Switzerland : Frontiers in microbiology , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 672738

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INTRODUCTION: Antibiotic overuse has caused the development of bacterial resistance, which is a major threat to public health. Intracellular metabolic processes are essential for maintaining the normal physiological activities of bacteria, and an increasing body of research has demonstrated a significant association between metabolic alterations and the development of drug resistance. Numerous studies have demonstrated that the addition of adjuvants can counteract bacterial antibiotic resistance. METHOD: Cystine treatment was verified RESULT: We confirmed that exogenous cystine increased the lethal effect of gentamicin against strain DISCUSSION: This study confirms that cystine enhances the antimicrobial efficacy of gentamicin against drug-resistant

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