getENRICH: a tool for the gene and pathway enrichment analysis of non-model organisms.

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Tác giả: Ajay Bhatia, Isha Chakraborty, Jitendra Narayan, Pranjal Pruthi, Nityendra Shukla

Ngôn ngữ: eng

Ký hiệu phân loại: 616.07563 Diseases

Thông tin xuất bản: England : Bioinformatics advances , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 672860

MOTIVATION: The Gene Ontology system facilitates the functional annotation of genes by categorizing them into specific biological processes, cellular components, and molecular functions. Despite numerous tools like DAVID and Enrichr, analysing non-model organisms remains challenging due to a lack of genetic information and available tools. RESULTS: To address this, we present getENRICH, a comprehensive tool for gene enrichment analysis tailored for non-model organisms. Available in both command-line and web-based graphical user interface (GUI) formats, getENRICH facilitates user-friendly interaction for gene dataset uploads, parameter configuration, and visualization. getENRICH employs hypergeometric distribution for AVAILABILITY AND IMPLEMENTATION: getENRICH is freely available under the MIT license, with the source code, documentation, and example datasets available on GitHub (https://github.com/jnarayan81/getENRICH) and the GUI version available at https://getenrich.igib.res.in/.
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