METHODS: A total of 112 patients with CRPA BSI and 112 patients with carbapenem-sensitive RESULTS: In the past 7 years, 7480 blood samples of CONCLUSION: Chronic lung disease, transplantation, multi-organ failure, prior CRPA infection, and prior carbapenems exposure are independent risk factors for the development of CRPA bacteremia. Sepsis or septic shock increases 28-day mortality. To investigate the molecular mechanisms of carbapenem-resistance of