Karst habitats are hotspots of diversity and endemism. Their naturally fragmented distributions across broad geographic landscapes have led to a complex array of smaller evolutionary ecosystems. Comprehensive biodiversity assessments of karst habitats have revealed that these ecosystems contain a high level of endemism. During a survey of cordycipitoid fungi in the karst region of southwest Guizhou, China, we identified and proposed two new species, based on morphology and multi-locus (nrSSU, nrLSU,