A cluster of RNA Polymerase II molecules is stably associated with an active gene.

• Tác giả: Raymond D Carter, Samantha Fallacaro, Yara I Haloush, Manya Kapoor, Mustafa Mir, Apratim Mukherjee, Puttachai Ratchasanmuang, Kareena Shankta
• Ngôn ngữ: eng
• Ký hiệu phân loại: 296.11645 Sources
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 674068

Tóm tắt

In eukaryotic nuclei, transcription is associated with discrete foci of RNA Polymerase II (RNAPII) molecules. How these clusters interact with genes and their impact on transcriptional activity remain heavily debated. Here we take advantage of the naturally occurring increase in transcriptional activity during Zygotic Genome Activation (ZGA) in