Cation Pretreatment Enables the Saline Stability of a Near-Infrared Sensor for Dopamine.

• Tác giả: Ardemis A Boghossian, Jing Chen, Benjamin Lambert, Xuewen Liu, Hanxuan Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 003.209 Historical, geographic, persons treatment of forecasting as a discipline
• Thông tin xuất bản: United States : ACS bio & med chem Au , 2025
• Bộ sưu tập: NCBI
• ID: 674086

Tóm tắt

Single-walled carbon nanotubes (SWCNTs) are wrapped with single-stranded DNA (ssDNA) to create near-infrared (NIR-II) fluorescent sensors for diverse analytes. However, the interaction between the negatively charged backbone of ssDNA and cations in biological saline alters fluorescence unpredictably. This susceptibility limits the application of these sensors in biological media. To address this limitation, this study develops a cation-pretreatment strategy that quenches the baseline fluorescence of ssDNA-SWCNTs to enable turn-on responses that are selectively triggered by analytes in saline. An initial screening of Na