Comprehensive Bioactive Compound Profiling of

• Tác giả: Taufik Muhammad Fakih, Raden Anita Indriyanti, Erni Maryam, Bambang Hernawan Nugroho, Maya Tejasari, Lelly Yuniarti
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.246 Dual-purpose breeds
• Thông tin xuất bản: New Zealand : Drug design, development and therapy , 2025
• Bộ sưu tập: NCBI
• ID: 674246

Tóm tắt

PATIENTS AND METHODS: Ethanol and ethyl acetate extracts were analyzed using Thin Layer Chromatography (TLC) and Liquid Chromatography-Mass Spectrometry/Mass Spectrometry (LC-MS/MS). Antioxidant activity was determined via DPPH radical scavenging and tyrosinase inhibition was compared against kojic acid. Molecular docking and molecular dynamics simulations explored binding interactions of Artocarpin and Sitosterol with matrix metalloproteinases (MMPs) and tyrosinase. RESULTS: Artocarpin and Sitosterol were identified as primary bioactive compounds. Ethanol extracts exhibited stronger tyrosinase inhibition (IC CONCLUSION: Artocarpin and Sitosterol from