Reversal of metformin's anti-proliferative effect in fission yeast

• Tác giả: Ari Gillespie, Tiffany Q Lim, Anne-Sophie Mehdorn, Michael Z Michael, Bridget A Mooney, Jonathan S Oakhill, Ayla Orang, Ashley J Ovens, Janni Petersen, Tingting Wang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 591.468 +Eggs
• Thông tin xuất bản: England : npj metabolic health and disease , 2025
• Bộ sưu tập: NCBI
• ID: 675208

Tóm tắt

Metformin is a well-tolerated drug frequently prescribed for managing type 2 diabetes. Extended metformin use has been linked to a significant decrease in cancer incidence across both diabetic and non-diabetic populations. Here we investigate the anti-proliferative effects of metformin on fission yeast