Advanced delivery systems for gene editing: A comprehensive review from the GenE-HumDi COST Action Working Group.

• Tác giả: Araceli Aguilar-González, Gloria Gonzalez Aseguinolaza, Karim Benabdellah, Lorea Blázquez, Houria Boulaiz, Alessia Cavazza, Marina Cortijo-Gutierrez, Berta de la Cerda, Lourdes R Desviat, Emilio M Garcia-Tenorio, Manuel A F V Gonçalves, Sergio Granados-Principal, Dhanu Gupta, Emily Haughton, Paula Heredia, Inmaculada Herrera, Cecilia Jiménez-Mallebrera, Mariana Köber, Duško Lainšček, Arístides López-Márquez, Yonglun Luo, Špela Malenšek, Loubna Mazini, Annarita Miccio, Francisco Martin Molina, Francisco J Molina-Estévez, Asma Naseem, Qianqian Ni, Kristina Pavlovic, Peter Pečan, Ling Peng, Álvaro Plaza Reyes, Eva Richard, Paula Rio, Victor Ronco, Rosario María Sánchez-Martín, Annalisa Santini, Irene Santos-Garcia, Marijana Stojanovic, Melita Vidaković, Dongnan Yan
• Ngôn ngữ: eng
• Ký hiệu phân loại: 109 Historical and collected persons treatment of philosophy
• Thông tin xuất bản: United States : Molecular therapy. Nucleic acids , 2025
• Bộ sưu tập: NCBI
• ID: 675440

Tóm tắt

In the past decade, precise targeting through genome editing has emerged as a promising alternative to traditional therapeutic approaches. Genome editing can be performed using various platforms, where programmable DNA nucleases create permanent genetic changes at specific genomic locations due to their ability to recognize precise DNA sequences. Clinical application of this technology requires the delivery of the editing reagents to transplantable cells