Wandering spleen (WS) is exceedingly rare and is attributed to the absence or maldevelopment of the spleen's anchoring ligaments. The diagnosis of WS in the emergency department poses a particular clinical challenge as the clinical presentation is highly variable from acute abdomen requiring immediate surgery to chronic indolent pain extending over years. Herein, we report the case of a 34-year-old nulliparous lady, who presented to the emergency department with left iliac fossa pain associated with vomiting, successfully diagnosed preoperatively using computerized tomography. A splenectomy was performed, and the patient achieved full recovery. Timely use of imaging aids emergency physicians in the early detection of wandering spleen. Early diagnosis allows spleen-preserving strategies and therefore prevents the life-threatening complications of postsplenectomy sepsis.