Photoenolization of

 0 Người đánh giá. Xếp hạng trung bình 0

Tác giả: Che-Wei Chang, Kuei-Chen Chang, Cheng-Chau Chiu, Hung-Hsuan Chiu, Chih-Ju Chou, Che-Ming Hsu, Pin-Gong Huang, Prem Kumar Keerthipati, Wen-Hsuan Lee, Yi-Hua Lee, Hsuan-Hung Liao, Shinje Miñoza, Sasirome Racochote, Darunee Soorukram

Ngôn ngữ: eng

Ký hiệu phân loại:

Thông tin xuất bản: United States : Journal of the American Chemical Society , 2025

Mô tả vật lý:

Bộ sưu tập: NCBI

ID: 675991

The enantioselective protonation of prochiral enolates is an ideal and straightforward platform to synthesize stereodefined α-tertiary esters, which are recurring motifs in a myriad of biorelevant molecules and important intermediates thereof. However, this approach remains onerous, particularly when dealing with α-unactivated esters and related acids, as enantioinduction on the nascent nucleophile necessitates peremptory reaction conditions, thus far only achieved via preformed enolates. A complementary and contra-thermodynamic catalytic strategy is herein described, where a transient photoenol, in the form of a ketene hemiacetal, is enantioselectively protonated with a chiral phosphoric acid (CPA). The prochiral photoketene hemiacetals are procured from excited
Tạo bộ sưu tập với mã QR

THƯ VIỆN - TRƯỜNG ĐẠI HỌC CÔNG NGHỆ TP.HCM

ĐT: (028) 36225755 | Email: tt.thuvien@hutech.edu.vn

Copyright @2024 THƯ VIỆN HUTECH