A phase I, single-center, randomized, open-label, three-period crossover study to evaluate the drug-drug interaction between ZSP1273 and oseltamivir in healthy Chinese subjects.

• Tác giả: Yingying Cao, Xuemei Chen, Jufang Huang, Hui Jiang, Haijun Li, Yiming Liu, Yanqing Pang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 220.4047 Original texts, early versions, early translations
• Thông tin xuất bản: United States : Antimicrobial agents and chemotherapy , 2025
• Bộ sưu tập: NCBI
• ID: 676200

Tóm tắt

ZSP1273 is a novel small-molecule anti-influenza drug that targets the RNA polymerase PB2 subunit, while oseltamivir is the first-line medication that inhibits neuraminidase. ZSP1273 showed high efficacy against human influenza viruses both