Nonbacterial respiratory pathogens are major acute respiratory infection (ARI) agents in children. We aimed to characterize the epidemiological changes in 11 common nonbacterial pathogens after easing COVID-19 restrictions in Zhejiang, China, to guide prevention and treatment. A retrospective study was conducted on children with ARIs at Children's Hospital, Zhejiang University School of Medicine in 2023, and epidemiological characteristics were analyzed for gender, age, month, sampling method, and immune status. In total, 59.48% of the children identified pathogens, and