Diagnostic performance of attenuation imaging versus controlled attenuation parameter for hepatic steatosis with MRI-based proton density fat fraction as the reference standard: a prospective multicenter study.

• Tác giả: Tamami Abe, Tomoyuki Akita, Yuichiro Eguchi, Yoichi Hiasa, Masashi Hirooka, Hiroko Iijima, Kento Imajo, Masayoshi Kage, Shigehiro Kokubu, Reiichiro Kondo, Takashi Kumada, Hidekatsu Kuroda, Fuminori Moriyasu, Atsushi Nakajima, Takashi Nishimura, Asako Nogami, Satoshi Oeda, Sadanobu Ogawa, Katsutoshi Sugimoto, Yasuaki Suzuki, Toshifumi Tada, Hirokazu Takahashi, Junko Tanaka, Hidenori Toyoda, Hirohisa Yano
• Ngôn ngữ: eng
• Ký hiệu phân loại: 627.12 Rivers and streams
• Thông tin xuất bản: Japan : Journal of gastroenterology , 2025
• Bộ sưu tập: NCBI
• ID: 676746

Tóm tắt

 BACKGROUND: Attenuation Imaging (ATI) and controlled attenuation parameter (CAP) are non-invasive ultrasound-based methods for diagnosing hepatic steatosis. However, reports on the clinical usefulness of ATI are limited. We aimed to compare the ability of ATI and CAP to diagnose hepatic steatosis with magnetic resonance imaging-based proton density fat fraction (MRI-PDFF) as the reference standard. METHODS: We performed a prospective multicenter study of 562 patients with chronic liver disease who underwent ATI, CAP, and MRI-PDFF. Patients with skin-to-liver capsule distance (SCD) ≤ 25 mm underwent CAP with an M probe
  those with SCD >
  25 mm underwent CAP with an XL probe. MRI-PDFF was used as the reference standard: S0 corresponds to MRI-PDFF <
  5.2%, S1 to 5.2% ≤ MRI-PDFF <
  11.3%, S2 to 11.3% ≤ MRI-PDFF <
  17.1%, and S3 to MRI-PDFF ≥ 17.1%. RESULTS: The correlation coefficients for ATI and MRI-PDFF stratified by body mass index (<
  30, ≥ 30 kg/m CONCLUSIONS: ATI is a more useful non-invasive method for diagnosing hepatic steatosis than CAP.