U.S. Immigration and Customs Enforcement (ICE) issues detainer requests to local law enforcement agencies to hold detainees suspected of being undocumented immigrants until they can be transferred into ICE custody. We examined the association between area-level detainer requests and self-rated health among Latine adults. We linked health data from Latine adults included in the 2017-2020 Behavioral Risk Factor Surveillance System (n = 69,386) to detainer requests per 1,000 non-citizens in core-based statistical areas, (n = 152 across 49 states). We fit logistic regression models of self-rated fair/poor health on detainer requests, adjusted for individual- and area-level confounders. In adjusted analyses, we found that Latine adults living in areas with the highest quartile of requests had 24% higher odds of fair/poor health (OR 1.24, 95% CI = 1.05,1.47) relative to those in the lowest quartile. Local law enforcement agencies should limit cooperation with federal immigrant agencies to protect the health of Latine communities.