Mechanism of the Dual Action Self-Potentiating Antitubercular Drug Morphazinamide.

• Tác giả: Courtney C Aldrich, Anthony D Baughn, Taylor A Crooks, Pooja Hegde, Michael D Howe, Ziyi Jia, Lev Ostrer, Nathan Schacht, Sang Vo
• Ngôn ngữ: eng
• Ký hiệu phân loại: 616.918801 Other diseases
• Thông tin xuất bản: United States : bioRxiv : the preprint server for biology , 2025
• Bộ sưu tập: NCBI
• ID: 677665

Tóm tắt

UNLABELLED: Pyrazinamide (PZA) is a cornerstone of first-line antitubercular drug therapy and is unique in its ability to kill nongrowing populations of SIGNIFICANCE STATEMENT: Pyrazinamide is the only antitubercular drug of its kind, capable of targeting persistent