Reliable and sensitive analytical platform to assess dietary exposure of pigs to mycotoxins and explore potential urinary biomarkers.

• Tác giả: Natalia Arroyo-Manzanares, Natalia Campillo, Ana Castell, José Fenoll, Antonio González, Vicente Rodríguez-Estévez, Josep Roquet, Santos Sanz-Fernández, Pilar Viñas
• Ngôn ngữ: eng
• Ký hiệu phân loại: 709.012 *To 4000 B.C.
• Thông tin xuất bản: Netherlands : Talanta , 2025
• Bộ sưu tập: NCBI
• ID: 678252

Tóm tắt

A reliable and sensitive analytical platform is proposed for the assessment of pig exposure to mycotoxins through the consumption of commercial feed. A total of 48 naturally contaminated feed and 55 urine samples collected from eight Spanish farms were analyzed using a fast and simple methodology based on solid-liquid extraction (SLE) or liquid-liquid extraction (LLE) and dispersive liquid-liquid microextraction (DLLME). High-performance liquid chromatography coupled to tandem mass spectrometry (HPLC-MS/MS) was used for the targeted analysis of 27 mycotoxins from different families in both matrices achieving limits of quantification in a range of 0.019-73.5 ng g