Combined antifungal therapy with immunostimulation for refractory cutaneous and peritoneal mucormycosis caused by Rhizopus microsporus.

• Tác giả: Alexandre Alanio, Mourad Benyamina, Louis Boutin, Marc Chaouat, Maité Chaussard, Hélène Corte, Maxime Coutrot, Alexandru Cupaciu, Charles Delale, Sarah Dellière, Benjamin Deniau, François Dépret, Emmanuel Dudoignon, Amélie Guihot, Lucie Guillemet, Samia Hamane, Fanny Lanternier, Chiheb Ben Maaouia, Thibault Mahévas, Rania Mhenni, Alexandre Pharaboz, Alexandra Serris, Thais Walter
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : Diagnostic microbiology and infectious disease , 2025
• Bộ sưu tập: NCBI
• ID: 678291

Tóm tắt

Mucormycosis is a fungal infection typically affecting immunocompromised patients. Here, we report a severe case of invasive cutaneous and peritoneal mucormycosis caused by Rhizopus microsporus, successfully treated with a combination of antifungal therapy, PD-1 inhibitor, and interferon-gamma. We highlight the importance of personalized immunotherapy in refractory cases of invasive mucormycosis.