Sensitive non-enzymatic sensing of creatinine in urine using a novel paper-based electroanalytical device.

• Tác giả: Yingying An, Jinqing Hong, Qing Lv, Wan Wang, Jinping Yue, Qing Zhang
• Ngôn ngữ: eng
• Thông tin xuất bản: Netherlands : Talanta , 2025
• Bộ sưu tập: NCBI
• ID: 678488

Tóm tắt

Accurate analysis of urinary creatinine levels is of great clinical significance. Non-enzymatic creatinine sensing systems (NECSs) have gained growing development because of higher stability and lower cost compared to enzymatic sensing systems. At present, there is a demand for simple approaches to develop NECSs with high sensitivity. In this study, we designed and fabricated an ingenious paper-based electroanalytical device for sensitive non-enzymatic creatinine sensing in urine. The device consisted of a paper-based chip and an integrated three-electrode system. The quantification of creatinine was performed based on the complexation of creatinine and copper sulfate (Cu