Bone dynamics in zebrafish on low- and high-frequency diets.

• Tác giả: Janna M Andronowski, Simon Bagatto, Kathryn Bisaha, Randi Depp, Rebekah Harden, Qin Liu, Richard L Londraville, Rachel Olson
• Ngôn ngữ: eng
• Ký hiệu phân loại: 630.2 Miscellany and scientific principles
• Thông tin xuất bản: England : Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology , 2025
• Bộ sưu tập: NCBI
• ID: 678517

Tóm tắt

 Zebrafish (Danio rerio) were fed high and low-frequency diets over 40 days to assess the effect of diet on bone parameters. Fish fed 3×/day (High) were significantly greater in total weight and length vs. fish fed 2×/week (Low
  <
 0.01). The High group had significantly higher vertebral bone density (p = 0.0009) and lower bone volume (p = 0.04) compared to the Low group. Scales from the Low group also had higher density of resorption lacunae in their scales (p = 0.02). We interpret these data to hypothesize that higher leptin titers associated with reduced calorie intake is generally catabolic to bone in zebrafish.