IL-33-activated ILC2s induce tertiary lymphoid structures in pancreatic cancer.

• Tác giả: Masataka Amisaki, David Artis, Manuel Baca, Vinod P Balachandran, Emmanuel M Bruno, Adrienne Kaya Chandra, Charlotte Cheng, Ashley S Doane, Rui Gardner, Mithat Gönen, Benjamin Greenbaum, Pablo Guasp, Abdul G Khan, Ivo C Lorenz, Stephen Martis, Taha Merghoub, Martina Milighetti, John Alec Moral, Elisabeth K Nyakatura, Zagaa Odgerel, Akihiro Ohmoto, Erin Patterson, George Payne, Charlotte Reiche, Luis A Rojas, Zachary M Sethna, Kevin Soares, Alexander Solovyov, Alexei V Tumanov, Olivia Vergnolle, Theresa Waters, Hiroshi Yano, Rebecca Yu, Abderezak Zebboudj, Siqi Linsey Zhang, Julia N Zhao
• Ngôn ngữ: eng
• Ký hiệu phân loại: 181.92 *Arabia
• Thông tin xuất bản: England : Nature , 2025
• Bộ sưu tập: NCBI
• ID: 678773

Tóm tắt

Tertiary lymphoid structures (TLSs) are de novo ectopic lymphoid aggregates that regulate immunity in chronically inflamed tissues, including tumours. Although TLSs form due to inflammation-triggered activation of the lymphotoxin (LT)-LTβ receptor (LTβR) pathway