Marine metal and metalloid pollution poses significant risks to elasmobranchs, especially in vital organs such as their sensory and visual systems. While contamination studies have traditionally focused on elasmobranch liver and muscle tissues, due to their significance in detoxification processes and human consumption, respectively, the eyes and brain of this group remain largely underexplored in ecotoxicology assessments. Metal and metalloid accumulation in these sensory organs may compromise key elasmobranch functions, impacting crucial survival behaviors, such as foraging and predator evasion. Detecting sublethal cellular effects caused by these contaminants in the eyes and brain employing biomarkers offers a pathway to assess pollutant sensory health effects before they extend to the organismal and population levels, although no studies have been carried out to date in this sense. This review compiles the current knowledge on metal and metalloid contamination in elasmobranch sensory systems, highlighting the need for further research to understand pollutant effects in these animals' ecological roles and inform conservation strategies.