Metabolomics Profiling Reveals Critical Roles of Indoxyl Sulfate in the Regulation of Innate Monocytes in COVID-19.

• Tác giả: Anne E Geller, Liqing He, Xiaoling Hu, Jiapeng Huang, Xipeng Ma, Kenneth McLeish, Samantha Morrissey, Yunke Wang, Raobo Xu, Jun Yan, Fang Yuan, Huang-Ge Zhang, Xiang Zhang
• Ngôn ngữ: eng
• Thông tin xuất bản: Switzerland : Cells , 2025
• Bộ sưu tập: NCBI
• ID: 680561

Tóm tắt

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is intricately related to the reprogramming of host metabolism. However, existing studies have mainly focused on peripheral blood samples and barely identified specific metabolites that are critically involved in the pathology of coronavirus disease 2019 (COVID-19). In the current small-scale study, we performed metabolic profiling in plasma (