Genomic Taxometric Analysis of Negative Emotionality and Major Depressive Disorder Highlights a Gradient of Genetic Differentiation across the Severity Spectrum.

• Tác giả: Javier de la Fuente, Garrett W Ennis, Travis T Mallard, Ted Schwaba, Elliot M Tucker-Drob, Camille M Williams
• Ngôn ngữ: eng
• Thông tin xuất bản: United States : medRxiv : the preprint server for health sciences , 2025
• Bộ sưu tập: NCBI
• ID: 680591

Tóm tắt

A core question in both human genetics and medicine is whether clinical disorders represent extreme manifestations of continuous traits or categorically distinct entities with unique genetic etiologies. To address this question, we introduce