Mitochondrial and Stress-Related Psychobiological Regulation of FGF21 in Humans.

• Tác giả: Alexander Behnke, Natalia Bobba-Alves, Quinn Conklin, Michio Hirano, Robert-Paul Juster, Catherine Kelly, Mangesh Kurade, Martin Picard, Caroline Trumpff
• Ngôn ngữ: eng
• Ký hiệu phân loại: 181.4 *India
• Thông tin xuất bản: United States : medRxiv : the preprint server for health sciences , 2025
• Bộ sưu tập: NCBI
• ID: 680595

Tóm tắt

FGF21 is a metabolic hormone induced by fasting, metabolic stress, and mitochondrial oxidative phosphorylation (OxPhos) defects that cause mitochondrial diseases (MitoD). Here we report that acute psychosocial stress alone (without physical exertion) decreases serum FGF21 by an average of 20% (