OBJECTIVE: To present and analyze the characteristics of the 100 most cited articles that used cerebral angiography for clinical evaluation and intervention. METHOD: Two researchers independently extracted articles from multiple databases and ranked them by citation count to create the "top 100 most-cited" list. RESULTS: The top 100 articles received a total of 115,243 citations. Twenty-one of the top 100 articles were published between 2006 and 2010. Most studied disorder was ischemic stroke ( CONCLUSION: Within the scope of this study, the following features may define a typical highly cited article-a randomized controlled clinical trial conducted in the United States that studied ischemic stroke, used cerebral angiography for diagnosis, and was published relatively recently in a high-impact journal by male first and senior authors.