Synthesis and evaluation of a targeted PET radioligand [

• Tác giả: Yu Liu, Jianjun Wang, Jingquan Xue, Wenjiang Yang, Ge Zhang, Yuxuan Zhang, Zhixiong Zhang
• Ngôn ngữ: eng
• Ký hiệu phân loại: 364.04 Special topics of criminology
• Thông tin xuất bản: England : Bioorganic & medicinal chemistry letters , 2025
• Bộ sưu tập: NCBI
• ID: 680799

Tóm tắt

Monoamine oxidase B (MAO-B) is a membrane-bound flavinase that plays an important role in the regulation of monoamine neurotransmission. Positron emission tomography (PET) provides a way to study the molecular mechanisms of MAO-B-related diseases and to evaluate the effects of drugs. In this study, we designed and synthesized [