OBJECTIVE: As China's ageing process accelerates, the annual prevalence of Metabolic Syndrome (MetS) among older Chinese adults continues to rise. This study seeks to assess the relationship between inflammatory markers, walking pace, and MetS in old Chinese adults. METHODS: This study utilised a cross-sectional design, drawing on data from the 2011 and 2015 waves of the China Health and Retirement Longitudinal Study (CHARLS) conducted by Peking University, encompassing 3587 older adults aged over 60. Data regarding inflammatory markers (CRP), walking speed, and variables associated with MetS (including waist circumference and blood pressure) were gathered. Multiple linear regression analysis was used to evaluate the relationship between CRP, walking speed, and MetS. RESULTS: In a cohort of 3587 older Chinese adults, slower walking speed (β = 0.414) and elevated CRP levels (β = 0.209) were significantly correlated with MetS, with the association persisting after controlling for confounding variables. Furthermore, females, urban residents, individuals with a higher BMI, and smokers exhibited an increased risk of developing MetS. CONCLUSION: Walking speed and CRP levels are critical determinants in evaluating the risk of MetS in older adults
improving walking speed and mitigating inflammation may contribute to a decreased risk of MetS.