Multiple casualty incident (MCI) are critical situations mandating an immediate response. Traditionally, members of emergency medical services (EMS) are notified about MCI through radio signals. However, communication failures can lead to delays in activation time of EMS operations. The use of bell signals is proposed as a solution to address these issues. This study uses a retrospective pre-post design evaluating the impact of the bell and radio signal on activation times for EMS operation in MCI. Data were collected from January 2020 to December 2023 and divided into two phases: radio signal use during 2020-2021 (pre-design), and bell signal use during 2022-2023 (post-design). In the event of MCI, the bell or radio is used primarily to alert medical personnel. After the MCI was recognized during the pre-design phase, the dispatcher utilized the radio signal, calling out all EMS personnel twice via radio at 171.425 MHz, with a one-minute interval between communication to notify them of the incident. The ED staff would be informed of these incidents through radio or telephone communication by EMS personnel. In the post-design phase, the dispatcher utilized the bell signal, ringing it three times to alert all staff. Activation time and equipment used by EMS during MCI operations was recorded for both phases. A total of 105 MCI with EMS operations were recorded. In the bell signal group, 52.1% (n = 199) of the participants were male. Mass transportation incidents accounted for the most of the MCI, comprising 73.6% in the bell signal group and 73.1% in the radio signal group. The average activation time was significantly shorter for the bell signal (1.54 min) compared to the radio signal (3.60 min) (P <
0.001). The average response time for the bell signal was 13.20 min, while the radio signal response time averaged 16.10 min (P = 0.042). Early activation time (less than 2 min after EMS dispatch) was significantly more likely in the Bell signal group (adjusted odds ratio, 1.25
95% confidence interval, 1.10-2.45) than in the Radio signal group. The activation and response times for EMS operations during MCI were significantly reduced by using bell signals to alert EMS staff.