Unveiling the antiviral inhibitory activity of ebselen and ebsulfur derivatives on SARS-CoV-2 using machine learning-based QSAR, LB-PaCS-MD, and experimental assay.

• Tác giả: Siwaporn Boonyasuppayakorn, Peerapon Deetanya, Lian Duan, Ryuhei Harada, Kowit Hengphasatporn, Phornphimon Maitarad, Masahiro Miura, Yuji Nishii, Thanyada Rungrotmongkol, Kanokwan Salamteh, Liyi Shi, Yasuteru Shigeta, Silpsiri Sinsulpsiri, Aphinya Suroengrit, Kittikhun Wangkanont, Patcharin Wilasluck, Qing-Feng Xu-Xu
• Ngôn ngữ: eng
• Ký hiệu phân loại: 526.63 Azimuth
• Thông tin xuất bản: England : Scientific reports , 2025
• Bộ sưu tập: NCBI
• ID: 681315

Tóm tắt

Ebsulfur and ebselen derivatives that were proven to be potent inhibitors against the main protease (M