Regulation of CXCR4 function by S1P

• Tác giả: Won-Ki Huh, Jae-Yeon Jeong, Hyun-Tae Kim
• Ngôn ngữ: eng
• Ký hiệu phân loại: 809.008 History and description with respect to kinds of persons
• Thông tin xuất bản: England : Cell communication and signaling : CCS , 2025
• Bộ sưu tập: NCBI
• ID: 681647

Tóm tắt

BACKGROUND: The trafficking of immune cells between lymphoid organs and circulation depends on gradients of CXCL12 and sphingosine-1-phosphate (S1P), mediated through their cognate receptors C-X-C chemokine receptor type 4 (CXCR4) and S1P receptor type 1 (S1P METHODS: Bimolecular fluorescence complementation (BiFC) assay, proximity ligation assay (PLA), and quantitative bioluminescence resonance energy transfer (BRET) assay were employed to detect CXCR4-S1P RESULTS: CXCR4-S1P CONCLUSIONS: This study identifies CXCR4-S1P