The Immunomodulatory Activity of High Doses of Vitamin D in Critical Care Patients with Severe SARS-CoV-2 Pneumonia-A Randomized Controlled Trial.

• Tác giả: Maria Lobo Antunes, Miguel Cardoso, Ana Godinho-Santos, Ana Moura Gonçalves, João Gonçalves, António Marinho, Bárbara Rodrigues, Sónia Velho
• Ngôn ngữ: eng
• Ký hiệu phân loại: 636.0885 Animal husbandry
• Thông tin xuất bản: Switzerland : Nutrients , 2025
• Bộ sưu tập: NCBI
• ID: 68227

Tóm tắt

Vitamin D receptor [VDR] expression promotes LL37 expression, possibly contributing to host defense. The hypothesis was that an increase in 25 hydroxyvitamin D [25vitD] could lead to enhanced VDR expression and increased LL-37 production, thereby contributing to improved prognosis in critically ill patients.