OBJECTIVE: As dental implanting becomes an increasing demand among patients with tooth loss, an efficient and effective training for students is to be necessary. In this case, we anticipate the possible application of virtual reality (VR) technology to pre-clinical implantation training (PCIT) in order to improve the students' learning efficiency and effectiveness. METHODS: The study divided 20 subjects into two groups on average-VR based PCIT (experimental group) and traditional PCIT (control group) with the completion of the background survey (BS) before PCITs, to guarantee no apparent backgroud variation including learning of oral implantology and VR technology, learning habits, interests and hobbies, RESULTS: The results show that from T-1 to T-2 period, the score of VR based PCIT increased significantly ( CONCLUSION: Compared with traditional PCIT, VR based PCIT has obvious influence on enhancing students' knowledge mastery, study willingness and learning efficiency.