INTRODUCTION: Aseptic hepatic abscesses are a highly uncommon phenomenon and even more rare in the spectrum of extraintestinal manifestations of inflammatory bowel disease. Part of the spectrum of "neutrophilic disease," both the pathogenesis and the optimal management of these aseptic abscesses remain unclear. In the context of inflammatory bowel disease, sometimes these abscesses appear despite normal endoscopic findings. CASE PRESENTATION: We describe a highly uncommon case of aseptic hepatic abscess formation in a patient with inflammatory bowel disease. CONCLUSION: In doing so, we investigated the concept of "aseptic abscess syndrome" as it relates to similar autoimmune conditions.